General questions

Q1: If a patient receives Dextrose 5% half Normal Saline with 20 meq of Potassium as IV fluid at 125mls/hour. How much dextrose in grams is he getting in 24hrs?

Q2: Patient X is 84 year old man who is in hospital for a back surgery.  The patient is getting hydromorphone PCA at 0.2mg/hour of basal rate, demand dose 0.1mg. lock-out every 6min, one hour limit 2.2mg/hour.   This patient used 5 on-demand bolus doses from the hydromorphone PCA, how much hydromorphone did L.N. get in 24 hours?

Q3: The bioavailability of levothyroxine is roughly 50%. A physician requests you for a dose recommendation to convert his home dose of 75mcg po daily to intravenous. Since the patient will be NPO for a while. What would be the appropriate intravenous dose?

Q4: An order is received to initiate Propofol at 10mcg/kg/min in a 56 YOM who weighs 180 pounds. What rate in mLs/hr should the Propofol be infused at? Propofol comes as 1000mg/100mls Lipid emulsion.

Q5: To prepare a 51.3 mEq of NaCl  1 liter bag. How many ml of 23.4% NaCl would you need? (Molecular weight of Na is 23 and Cl is 35.5)  

Q6: When 50 gms 5% of lidocaine cream is mixed with 90 gm of 0.5 % hydrocortisone cream, what percent of lidocaine and hydrocortisone are there in the final product?

Q7: When 50 gms 5% of lidocaine cream is mixed with 90 gm of 0.5 % lidocaine cream, what percent of lidocaine is there in the final product?

Q8: An order is received for heparin 18 units per kg per hour on a patient whose weight is 125lb. The IV bag comes as a concentration of 50 units /mL. Calculate the infusion rate in terms of mL/hr.

Q9: Injectable Sulfamethoxazole/Trimethoprim comes as 400mg/80mg/5ml. Physician requests you to dose a Sulfamethoxazole/Trimethoprim intravenously for PCP. You know the dose is 15mg/kg/day (based on TMP component) divided q6h. How many milliliters of Sulfamethoxazole/Trimethoprim of 400mg/80mg/5ml would you need for single dose? Patient weighs 80Kg.

Q10: What is the weight of 1500 ml of serum protein whose specific gravity is 1.27?

Q11: What is the mEq/ml (Milliequivalents) of 50% Magnesium Sulfate? (Molecular Weight of MgSO4 is 120.4g/mol)

Q12: What is the Osmolarity in mOsm/L of 40mEq of KCl in 100ml sterile water? (Molecular Weight of KCl is 74.5gm/mol)?

Q13: A Physician orders amiodarone 1 mg/min for six hours, then 0.5 mg/min thereafter. The patient’s weight is 170 lbs. The concentration of the IV bag comes as 1.8 mg per ml. Calculate the infusion rate in mL/hr.  

Q14: If a patient is getting NS IVF at 120mls/hr. How much Sodium Chloride in grams is this patient getting in 24 hours? NS is 0.9% sodium chloride.

Q15: A Physician orders Dobutamine HCl IV infusion at 5 mcg/kg/min. Dobutamine HCl is available as 500 mg in 250 mL of D5W. The patient weighs 68 kg. Calculate the infusion rate in mL/hr.

Q16: A physician ordered dopamine 25 ug/kg IV infusion for 1 hours. The patient weighs 170 LB. The concentration of dopamine is 10 ug/mL. The drop factor is 20 gtt/mL. What is the IV flow rate in drops?

Q17: An order request for 5% aminoa acid 15% dextrose premixed parenteral nutrition solution, 2 L at 83 mls/hr. Howeve, the pharmacist only has a 20% detrose. How many mL of 20% dextrose would you need to provide the same amount of dextrose in 24 hours. 

Q18: A physician orders 500 gms of albumin, how many milliliters of 10 % albumin is required to fill this order?

Q19: The dose of drug X is 350 mg/m². For a patient weighing 175 lb and measuring 170 cm in height, how many milligrams of this drug are required?

Q20: A patient undergoing chemotherapy requires a medication dosed at 5 mg/kg for the first 3 days, followed by 2 mg/kg for the next 4 days. If the patient weighs 80 kg, calculate the total amount of medication required over the entire treatment period.

Q21: A physician orders an IV infusion of 1,500 mL of D5W to be administered over 10 hours. After 3 hours, the patient develops an adverse reaction and the infusion rate is increased to 200 mL/hour for the remaining time. Calculate the total volume of D5W infused and the average rate over the entire duration.

Q22: A pediatric patient is prescribed an antibiotic at a loading dose of 30 mg/kg, followed by a maintenance dose of 15 mg/kg every 8 hours. If the child weighs 12 kg, calculate the total amount of antibiotic to be administered in the first 24 hours.

Q23: You have a stock solution containing 1,000 mg of a drug in 500 mL of solution. You need to prepare a diluted solution of 250 mg in 100 mL. How much of the stock solution should be used, and how much diluent is needed to achieve this concentration?

Q24: A patient requires chemotherapy at a dosage of 80 mg/m². If the patient's body surface area (BSA) is calculated to be 2.2 m², but the physician decides to reduce the dose to 75% due to potential side effects, what is the final dose in milligrams that should be administered?

Q25: A patient is prescribed two medications: Drug A at a dosage of 100 mg/m² and Drug B at a dosage of 50 mg/kg. The patient has a body surface area (BSA) of 1.9 m² and weighs 70 kg.

1. Calculate the total dose of Drug A the patient should receive.
2. Calculate the total dose of Drug B the patient should receive.
3. If Drug A and Drug B have a known interaction that requires a 25% reduction in the dose of Drug A when administered together, what is the final dose of Drug A that should be given to the patient?

Naplex preparation